The artist has given the entirety of his £25,000 honor prize money to the trust for venues, which operates to save the Britain's grassroots live music spots.
The star was awarded the award on 16 October as his latest record the album was declared the best record of the last 12 months.
Fender has decided to give the cash to the trust, in acknowledgment of the essential function local spots fulfilled in his initial steps.
"I personally couldn't be pursuing my current career if it wasn't for all the shows I played around the area, and further afield, when I was starting out," remarked Fender. "These locations are renowned, but they are facing challenges."
Beginning in 2023, over 150 of these venues have permanently closed – roughly 16 percent of the entire UK sector.
Recently, major artists including Pulp, Coldplay, the singer Katy Perry and Sheeran have all aided the Music Venues Trust in its efforts to help venues survive, by applying a modest fee to their ticket prices, which benefits smaller concert halls.
He also participated, raising over £100k on his live tour to help 38 local spots across the UK.
The money helped locations that were confronting imminent closure due to challenges caused by flooding, fire incidents and personal losses, as well as regulatory hurdles, legal disputes and neighbor objections.
Additional spaces were granted funding support in upgrading facilities and technical equipment that directly benefitted artists and audiences.
"The concept that funds from shows in major spaces supports the local stages, where it begins for artists like me, is just common sense," Sam Fender has stated.
Fender is far from the only musician to contribute his Mercury Prize funds to good deeds.
Back when they won the award in the mid-90s for their record the album, vocalist Cocker stated that the group would contribute their winnings to the organization the charity.
In 2002, rapper and singer Ms Dynamite divided her prize across several good causes, like the NSPCC and a Sickle Cell organization.
"Additionally, I donated a grand to Highgate Newtown, to their gymnastics program, because I trained in gymnastics when I was growing up and they needed new equipment," Ms Dynamite told the media.
Previously, Ezra Collective contributed their winnings to the community center that nurtured their group, as well as other independent music bodies.
And the 1994 recipients M People gave their winnings to a MS organization after a friend was diagnosed the disease.
"Winning was sufficient," said vocalist the singer. "The money was the cherry on top but we didn't require the cherry, because we had the main prize. So our victory touched another person's life."
Last week, the Music Venues Trust shared it had rescued a couple of local spots in that region, by bringing them into local control.
The Joiners in that area and the second in Bristol were bought under the Own Our Venues scheme, which is funded by a national body and supporters who buy "ownership units" in the properties.